Release 3.2 of the Next-Generation IEDB Tools Website is now live! This release brings a major update to the PVC tool, allowing for class II predictions, as well as other enhancements throughout.
Head over to https://nextgen-tools.iedb.org/ to try it out!
Release notes - 3.2 (Dec 11, 2025)
- Peptide Variant Comparison (PVC)
- T Cell - class II predictions incorporated
- Scatter plots for ICERFIRE
- PHBR enhancements
- New input format supported to allow auto-calculation of mutated positions
- Pipeline integration improvements (piping mut_peptide & ref_peptide from mutated peptide generator to PHBR)
- Updated Standalones
- Bug fixes and performance improvements
- Memory leak fixes
- Validation improvements in PHBR and PVC
- Error message improvements throughout