We are excited to announce that the initial release of the Next-Generation IEDB Tools Website is now open to the public! This is a complete redesign of the IEDB Analysis Resource with an emphasis on usability, simplicity, and tool integration.
Head over to https://nextgen-tools.iedb.org/ to try it out!
Release notes - 1.0 (Feb 14, 2023)
- Streamlined and consistent user interface with tools for power users
- Pipelines allow for chaining together various tools in a single run
- Available tools:
- T cell class I application includes most tools related to MHC class I epitope prediction and analysis and allows the running of multiple tools simultaneously
- MHC-I binding
- MHC-I processing
- MHC-I immunogenicity
- Clustering provides a way to group peptide sequences based on sequence identity
- PEPMatch allows for the efficient search for closely related peptides in several common reference proteomes
- T cell class I application includes most tools related to MHC class I epitope prediction and analysis and allows the running of multiple tools simultaneously
- New API to support pipelining and predictions for large datasets
- New, rich user documentation is available at Next-Generation (NG) IEDB Tools Documentation — Next-Generation (NG) IEDB Tools 0.1.0 documentation
- Follow-up releases planned on a 3-month cycle
- Next release will focus on enhancing speed
- Additional tools will be migrated from the legacy site (https://tools.iedb.org) over the next iterations
Release notes - 1.0.1 (Jun 2, 2023)
- PEPMatch updated to version 0.8.3
- Peptides with 0 matches are no longer shown in the output
- Pipeline map updated to include ‘Run’ button and make controls for adding steps more intuitive
- Resource limits implemented on several tools to prevent server overload
- Several new conditions tested to provide users with meaningful warning and error messages
Release notes - 1.0.2 (Jun 15, 2023)
- bug fixed in smm & smmpmbec IC50 and percentile calculations for lengths other than 9
- backend API functionality enhancements and stability improvements
Release notes - 1.0.3 (Jun 20, 2023)
- bug fixed in immunogenicity tool for ‘custom’ and ‘by allele’ options