The IEDB team has performed multiple meta-analysis using data collected in the IEDB. The articles studied infectious diseases, such as influenza and malaria, autoimmune diseases, and cancer associated antigens, among other topics.
The complete list of meta-analysis is found below.
- Targets of influenza human T-cell response are mostly conserved in H5N1 (2025)
39714185.pdf (1.7 MB) - Pre-existing SARS-2-specific T cells are predicted to cross-recognize BA.2.86 (2024)
38070502.pdf (3.6 MB) - T Cell Responses to SARS-CoV-2 (2023) 36750314.pdf (494.5 KB)
- A meta-analysis of epitopes in prostate-specific antigens identifies opportunities and knowledge gaps (2023) 37679223.pdf (1.7 MB)
- Correlative CD4 and CD8 T-cell immunodominance in humans and mice: Implications for preclinical testing (2023) 37726420.pdf (2.7 MB)
- The MegaPool Approach to Characterize Adaptive CD4+ and CD8+ T Cell Responses (2023) 37966108.pdf (876.9 KB)
- Trans-ancestral fine-mapping of MHC reveals key amino acids associated with spontaneous clearance of hepatitis C in HLA-DQβ1 (2022) 35090584.pdf (2.2 MB)
- Defining antigen targets to dissect vaccinia virus and monkeypox virus-specific T cell responses in humans (2022) 36463861.pdf (1.7 MB)
- Lack of evidence of significant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens (2022) 34998242.pdf (1.2 MB)
- An immunologically friendly classification of non-peptidic ligands (2021) 33772585.pdf (798.5 KB)
- Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases (2021) 33521695.pdf (613.4 KB)
- SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19 (2021)
34237248.pdf (1.2 MB) - A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2 (2020) 32183941.pdf (2.0 MB)
- Epitope prediction and identification- adaptive T cell responses in humans (2020) 33131981.pdf (427.3 KB)
- Comprehensive Review of Human Plasmodium falciparum-Specific CD8+ T Cell Epitopes (2019) 31451291.pdf (462.3 KB)
- Human T Cell Response to Dengue Virus Infection (2019) 31552052.pdf (1021.6 KB)
- A survey of known immune epitopes in the enteroviruses strains associated with acute flaccid myelitis (2019) 31451291.pdf (462.3 KB)
- Investigation of outbreak-specific nonsynonymous mutations on Ebolavirus GP in the context of known immune reactivity (2018) 30581874.pdf (708.5 KB)
- A Review on T Cell Epitopes Identified Using Prediction and Cell-Mediated Immune Models for Mycobacterium tuberculosis and Bordetella pertussis (2018) 30555469.pdf (1.2 MB)
- Identifying Candidate Targets of Immune Responses in Zika Virus Based on Homology to Epitopes in Other Flavivirus Species (2016) 28018746.pdf (942.8 KB)
- Ebola: an analysis of immunity at the molecular level (2015) Ponomarenko et al 2015.pdf (413.1 KB)
- Analysis of Human RSV Immunity at the Molecular Level: Learning from the Past and Present (2015) 26001197.pdf (2.1 MB)
- The Use of the Immune Epitope Database to Study Autoimmune Epitope Data Related to Alopecia Areata (2015) 26551944.pdf (3.7 MB)
- Substantial gaps in knowledge of Bordetella pertussis antibody and T cell epitopes relevant for natural immunity and vaccine efficacy (2014) 24530743.pdf (1.0 MB)
- Conservancy of mAb Epitopes in Ebolavirus Glycoproteins of Previous and 2014 Outbreaks (2014) 25642381
- Ebola virus related immune epitope data curated in the IEDB (2014) Ponomarenko et al 2014.pdf (503.5 KB)
- Analysis of Ebola virus envelope glycoprotein (GP): Prediction of HLA class II restricted T cell epitopes
- Positional bias of MHC class I restricted T-cell epitopes in viral antigens is likely due to a bias in conservation (2013) 23357871.pdf (442.2 KB)
- Navigating diabetes-related immune epitope data: resources and tools provided by the Immune Epitope Database (IEDB) (2013) 25140192.pdf (3.2 MB)
- A molecular view of multiple sclerosis and experimental autoimmune encephalitis: What can we learn from the epitope data? (2013) 24365494.pdf (416.0 KB)
- Strategies to Query and Display Allergy-Derived Epitope Data from the Immune Epitope Database (2012) 23172234.pdf (634.6 KB)
- A comparison of epitope repertoires associated with myasthenia gravis in humans and nonhuman hosts (2012) 23243503.pdf (1.6 MB)
- A Meta-Analysis of the Existing Knowledge of Immunoreactivity against Hepatitis C Virus (HCV) (2012) 22675428.pdf (1.1 MB)
- Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available data (2011) 21403821.pdf (579.9 KB)
- Meta-analysis of all immune epitope data in the Flavivirus genus: inventory of current immune epitope data status in the context of virus immunity and immunopathology (2010) 20565291.pdf (790.7 KB)
- Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population (2009) 19918065.pdf (875.7 KB)
- Classification of the universe of immune epitope literature: representation and knowledge gaps (2009)19774228.pdf (414.4 KB)
- Meta-analysis of immune epitope data for all Plasmodia: overview and applications for malarial immunobiology and vaccine-related issues (2009) 19149776.pdf (144.5 KB)
- Swine flu epitope analysis version 2.0 (2009)
- Swine Flu Analysis
- Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum (2008) 18251694.pdf (1.5 MB)
- Ab and T cell epitopes of influenza A virus, knowledge and opportunities (2007) 17200302.pdf (318.3 KB)
- Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database (2007) 18068490.pdf (48.9 KB)
- An analysis of the epitope knowledge related to Mycobacteria (2007) 18081934.pdf (342.8 KB)